The White group is an interdisciplinary team that applies principles grounded in electrochemistry to advance understanding of a wide variety of physical systems. Systems currently investigated within the group span the physical, analytical and biological sciences. These include nano-pore/pipette based sensing, measuring and delivery of nanoscale particles; protein ion channel electrical measurements of nucleic acids; theoretical and electrochemical scanned probe investigations of solid-state batteries; experimental measurements and theoretical analysis of ionic transport in confined geometries; and fundamental studies of electrochemically generated nanobubbles. See below for our latest publications, and the research section for more details on our research interests.
Observing Transient Bipolar Electrochemical Coupling on Single Nanoparticles Translocating through a Nanopore
C. Han, R. Hao, Y. Fan, M. A. Edwards, H. Gao, and B. Zhang
Langmuir, Just Accepted Manuscript. DOI: 10.1021/acs.langmuir.9b01255
Y. Kawamata, J. C. Vantourout, D. P. Hickey, P. Bai, L. Chen, Q. Hou, W. Qiao, K. Barman, M. A. Edwards, A. F. Garrido-Castro, J. N. deGruyter, H. Nakamura, K. W. Knouse, C. Qin, K. J. Clay, D. Bao, C. Li, J. T. Starr, C. Garcia-Irizarry, N. Sach, H. S. White, M. Neurock, S. D. Minteer, and P. S. Baran
J. Am. Chem. Soc., 2019, 141 (15), pp 6392–6402
Voltammetric Determination of the Stochastic Formation Rate and Geometry of Individual H2, N2, and O2 Bubble Nuclei
M. A. Edwards, H. S. White, H. Ren
ACS Nano, Article ASAP. DOI: 10.1021/acsnano.9b01015
γ-Hemolysin Nanopore Is Sensitive to Guanine-to-Inosine Substitutions in Double-Stranded DNA at the Single-Molecule Level
Cherie S. Tan, Aaron M. Fleming , Hang Ren , Cynthia J. Burrows, and Henry S. White
J. Am. Chem. Soc., 2018, 140 (43), pp 14224–14234.
Nanoscale electrochemical kinetics & dynamics: the challenges and opportunities of single-entity measurements
Martin Edwards, Donald Robinson, Hang Ren, Cameron Cheyne, Cherie Tan, and Henry S. White.
Faraday Discuss., 2018, 210, 9-28.
Effects of Instrumental Filters on Electrochemical Measurement of Single‐Nanoparticle Collision Dynamics
Donald Robinson, Martin A. Edwards, Hang Ren, and Henry S. White
ChemElectroChem,2018, 5, 3059.
Álvaro Moreno Soto, Sean R. German, Hang Ren, Devaraj van der Meer, Detlef Lohse, Martin A. Edwards, and Henry S. White
Langmuir, 2018, 34 (25), pp 7309–7318.
Sean R. German, Martin A. Edwards, Hang Ren, and Henry S. White
J. Am. Chem. Soc., 2018, 140 (11), pp 4047–4053.
Single-Molecule Titration in a Protein Nanoreactor Reveals the Protonation/Deprotonation Mechanism of a C:C Mismatch in DNA
Hang Ren, Cameron G. Cheyne, Aaron M. Fleming, Cythia J. Burrows, and Henry S. White
J. Am. Chem. Soc., 2018, 140, 15, 5153-5160.
Nanopore Opening at Flat and Nano-Tip Conical Electrodes during Vesicle Impact Electrochemical Cytometry
Xianchan Li, Lin Ren, Johan Dunevall, Daixin Ye, Henry S. White, Martin A. Edwards, and Andrew G. Ewing
ACS Nano, 2018, 12(3):3010-3019.
Tao Zeng, Aaron M. Fleming, Yun Ding, Hang Ren, Henry S. White, Cynthia J. Burrows
J. Org. Chem., 2018, 83 (7), pp 3973–3978.
Exploring the suitability of different electrode materials for hypochlorite quantification at high concentration in alkaline solutions
Featured in Spotlights, a new initiative of The Journal of Physical Chemistry Letters designed to expand awareness for physical chemistry by presenting accessible plain-language summaries of select articles in each issue.
H. Ren, S. R. German, M. A. Edwards, Q. Chen, and H. S. White
Interrogation of Base Pairing of the Spiroiminodihydantoin Diastereomers Using the α-Hemolysin Latch
Tao Zeng, Aaron M. Fleming, Yun Ding, Henry S. White, and Cynthia J. Burrows
Biochemistry, 2017, 56 (11), 1596–1603.
Dynamics of a DNA Mismatch Site Held in Confinement Discriminate Epigenetic Modifications of Cytosine
Robert P. Johnson, Aaron M. Fleming, Rukshan T. Perera, Cynthia J. Burrows, and Henry
J. Am. Chem. Soc., 2017, 139 (7), 2750–2756.
Yuwen Liu, Martin A. Edwards, Sean R. German, Qianjin Chen, and Henry S. White
Langmuir, 2017, 33 (8), 1845–1853.
Stephen M Oja, Donald A. Robinson, Nicholas J. Vitti, Martin A. Edwards, Yuwen Liu,
Henry S. White, and Bo Zhang
J. Am. Chem. Soc., 2017, 139 (2), 708–718.
Kinetics of T3-DNA Ligase-Catalyzed Phosphodiester Bond Formation Measured Using the α-Hemolysin Nanopore
Cherie S. Tan, Jan Riedl, Aaron M. Fleming, Cynthia J. Burrows, and Henry S. White
ACS Nano, 2016, 10 (12), 11127–11135.
A. Alec Talin, Dmitry Ruzmetov, Andrei Kolmakov, Kim McKelvey, Nicholas Ware, Farid
El Gabaly, Bruce S. Dunn, and Henry S. White
ACS Appl. Mater. Interfaces, 2016, 8 (47), 32385–32391.
Wen-Jie Lan, Martin A. Edwards, Long Luo, Rukshan T. Perera, Xiaojian Wu, Charles
R. Martin, and Henry S. White
Acc. Chem. Res., 2016, 49 (11), 2605–2613.
Sean R. German, Martin A. Edwards, Qianjin Chen, and Henry S. White
Nano. Lett., 2016, 16 (10), 6691–6694.
Kim McKelvey, Martin A. Edwards, and Henry S. White
J. Phys. Chem. Lett., 2016, 7, 3920–3924.
Redox Cycling in Nanogap Electrochemical Cells. The Role of Electrostatics in Determining the Cell Response
Qianjin Chen, Kim McKelvey, Martin A. Edwards, and Henry S. White
J. Phys. Chem. C, 2016, 120 (31), 17251–17260.