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  1. Bruender, N. A., and Bandarian, V. (2016) SkfB abstracts hydrogen atom from Ca on SkfA to initiate thioether cross-link formation. Biochemistry, 55, 4131-4134 
  2. Bruender, N. A., Wilcoxen, J., Britt, R. D., and Bandarian, V. (2016) Biochemical and spectroscopic characterization of a radical S-adenosyl-L-methionine enzyme involved in the formation of a peptide thither cross-link. Biochemistry,55, 2122-2134.
  3. Nelp, M. T. Song, Y., Wysocki, V. H., and Bandarian, V. (2016) A Protein-Derived Oxygen is the Source of the Amide Oxygen of Nitrile Hydratases. J. Biol. Chem. 291:  7822-7829  (Selected as Paper of the Week)
  4. Skinner OS, Havugimana PC, Haverland NA, Fornelli L, Early BP, Greer JB, Fellers RT, Durbin KR, Do Vale LH, Melani RD, Seckler HS, Nelp MT, Belov ME, Horning SR, Makarov AA, LeDuc RD, Bandarian V, Compton PD, Kelleher NL. (2016) An informatics framework for decoding protein complexes by top-down mass spectrometry.  Nat. Methods, 13, 237-240.
  5. Song, Y., Nelp, M. T., Bandarian, V., and Wysocki, V. H. (2015) Refining the Structural Model of a Heterohexameric Protein Complex: Surface Induced Dissociation and Ion Mobility Provide Key Connectivity and Topology Information. ACS Cent. Sci.1, 477-487. (Featured on the cover of the journal)
  6. Bandarian, V., Drennan, C. L. (2015) Radical-Mediated Ring Contraction in the Biosynthesis of 7-Deazapurines. Curt. Opin. Struct. Biol. 23, 477-487.
  7. Young, A. P. , Bandarian, V. (2015) Mechanistic Studies of the Radical S-Adenosyl-l-methionine Enzyme 4-Demethylwyosine Synthase Reveal the Site of Hydrogen Atom Abstraction. Biochemistry 2015, 54, 3569–3572.
  8. Nelp, M. T., Bandarian, V. (2015) A Single Enzyme Transforms a Carboxylic Acid into a Nitrile through an Amide Intermediate. Angew. Chem. Int. Ed. Engl. 2015, doi:10.1002/anie.201504505.
  9. Bruender, N. A., Young, A. P., Bandarian, V. (2015) Chemical and Biological Reduction of the Radical SAM Enzyme CDG Synthase. Biochemistry, 54:2903–2910.
  10. Miles ZD, Myers WK, Kincannon WM, Britt RD, and Bandarian V (2015) Biochemical and Spectroscopic Studies of Epoxyqueuosine Reductase: A Novel Iron-Sulfur Cluster- and Cobalamin-Containing Protein Involved in the Biosynthesis of Queuosine. Biochemistry 2015, doi:10.1021/acs.biochem.5b00335.
  11. Lajoie, D. M., Roberts, S. A., Zobel-Thropp, P. A., Delahaye, J. L., Bandarian, V., Binford, G. J., and Cordes, M. H.  (2015) Variable substrate preference among phospholipase D toxins from Sicariid spiders, J. Biol. Chem.,290, 10994-11007.
  12. Miles, Z. D., Roberts, S. A., McCarty, R. M., and Bandarian V.  (2014) Biochemical and Structural Studies of QueD Reveal the Molecular Basis of Catalytic Promiscuity within the Tunnel Fold Superfamily, J Biol. Chem., 289, 23641-23652.
  13. Nelp, M. T., Astashkin, A. V., Breci, L. A., McCarty, R. M., and Bandarian V. (2014)  Nitrile Hydratase Activity and Post-Translational Modifications Derive Solely from the Active Site Containing Alpha Subunit., Biochemistry, 53, 3990-3994.
  14. Dowling, D. P., Bruender, N. A., Young, A. P., McCarty,  R. M., Bandarian, V., and Drennan, C. L.  (2014)  Radical SAM enzyme QueE defines a new minimal core fold and metal-dependent mechanism, Nat Chem Biol, 10, 106-112.
  15. Young, A. P., and Bandarian, V.  (2013) Radical mediated ring formation in the biosynthesis of the hypermodified tRNA base wybutosine, Curr Opin Chem Biol, 17, 613-618.
  16. Lajoie, D., Zobel-Thropp, P., Kumirov, V., Bandarian, V., Binford, G., Cordes, M.H.J. (2013) Brown spider venom converts lysophosphatidylcholine and sphingomyelin to cyclic phosphates, PlosONE, 8(8):e72372.
  17. McCarty, R.M., Krebs, C., and Bandarian, V.  (2013) Spectroscopic, steady-state kinetic, and mechanistic characterization of the radical SAM enzyme QueE, which catalyzes a complex cyclization reaction in the biosynthesis of 7-deazapurines, Biochemistry. 52, 188-198. PMID: 23194065
  18. Bandarian, V. (2012) Radical SAM enzymes involved in the biosynthesis of purine-based natural products, Biochim Biophys Acta, 1824, 1245-1253. PMID: 22902275
  19. McCarty, R.M., and Bandarian, V. (2012) Biosynthesis of pyrrolopyrimidines, Bioorg Chem,43, 15-25.  PMID: 22382038
  20. Young, A.P., and Bandarian, V. (2011) Pyruvate is the source of the two carbons that are required for formation of the imidazoline ring of 4-demethylwyosine, Biochemistry, 50, 10573-10575.  PMCID: PMC3232322
  21. Jenkins, J. L., Krucinska, J., McCarty, R. M., Bandarian, V., and Wedekind, J. E. (2011) Comparison of a preQ1 riboswitch aptamer in metabolite-bound and free states with implications for gene regulation, J. Biol. Chem., 28, 24626-24637. PMCID: PMC3137038 
  22. Miles, Z. D., McCarty, R. M., Molnar, G., and Bandarian, V.  (2011) Discovery of oQ reductase reveals parallels between halorespiration and tRNA modification, Proc. Nat. Acad. Sciences USA, 108, 7368-7372. PMCID: PMC3088584
  23. Blackwell, A. E., Dodds, E. D., Bandarian, V., and Wysocki, V. H.  (2011)  Revealing the quaternary substructure of a heterogeneous noncovalent protein complex through surface-induced dissociation, Anal. Chemistry, 83, 2862-2865. PMCID: PMC3343771
  24. McCarty, R. M., Somogyi, A., Lin, G., Jacobsen, N. E., and Bandarian, V.  (2009) The deazapurine biosynthetic pathway revealed:  In vitro enzymatic synthesis of preQ0 from guanosine 5’-triphosphate in four steps, Biochemistry, 48, 3847-3852. (Accelerated publication) PMCID: PMC2693876
  25. Spitale, R. C., Torelli, A. T., Krucinska, J., Bandarian, V. and Wedekind, J. E.  (2009) The structural basis for recognition in the preQ0 metabolite by an unusually small riboswitch aptamer domain, J. Biol. Chem., 284, 11012-11016. PMCID: PMC2670106
  26. McCarty, R. M., Somogyi, A. and Bandarian, V.  (2009)  Escherichia coli QueD is a 6-carboxy-5,6,7,8-tetrahydropterin synthase, Biochemistry, 48, 2302-2303. PMCID: PMC3227869
  27. Spoonamore, J. E., Heroux, A., Roberts, S. A. and Bandarian, V.  (2008) Structure of a 6-pyruvoyltetrahydropterin synthase homolog from Streptomyces coelicolor, Acta Crystallographica Section F, 64, 875-879. PMCID: PMC2564891
  28. McCarty, R. M. and Bandarian, V.  (2008) Deciphering deazapurine biosynthesis: pathway for pyrrolopyrimidine nucleosides toyocamycin and sangivamycin, Chemistry and Biology, 28, 790-798. (Also featured on the Cover). PMCID: PMC2603307
  29. Bandarian, V.  (2008) Delivery of tailor-made cobalamin to methylmalonyl-CoA mutase, Nature Chemical Biology, 4, 158-159. PMID:18277972 (PMCID: PMC Not Required)
  30. Spoonamore, J. E. and Bandarian, V. (2008) Understanding functional divergence in proteins by studying intragenomic homologs, Biochemistry, 47, 2592-2600. PMID:18281960 (PMCID: PMC Not Required)
  31. Morrison, S. D., Roberts, S. A., Zegeer, A. B., Montfort, W. R., and Bandarian, V. (2008) A new use for a familiar fold:  The X-ray crystal structure of GTP-bound GTP cyclohydrolase III from Methanocaldococcus jannaschii reveals a two metal ion catalytic mechanism, Biochemistry, 47, 230-242. (Designated “Hot Article”) PMID:18052207 (PMCID: PMC Not Required)
  32. Quaranta D., McCarty, R., Bandarian, V., and Rensing, C.  (2007)  The copper-inducible cin operon encodes an unusual methionine-rich azurine like protein and a preQ0 reductase in Pseudomonas putide KT 2440, J. Bacteriol., 189, 5361-5371. PMCID: PMC1951875
  33. Spoonamore, J. E., Dahlgran, A. L., Bandarian, V.  (2006) Evolution of new function in the GTP cyclohydrolase II proteins of Streptomyces coelicolor, Biochemistry, 45, 12144-12155. (Designated “Hot Article”) PMID:17002314
  34. Poyner, R., Anderson, M. S., Bandarian, V., Cleland, W. W., Reed, G. H.  (2006) Probing nitrogen-sensitive steps in the free-radical-mediated deamination of amino alcohols by ethanolamine ammonia-lyase,  J. Am. Chem. Soc., 128, 7120-7121. PMCID: PMC16734439
  35. Bandarian, V. and Matthews, R. G. (2004) in Encyclopedia of Biological Chemistry, Vol. 1, pp145-151, Elsevier, Inc. 
  36. Bandarian, V. and Matthews, R. G.  (2004)  Measurement of energetics of conformational change in the cobalamin-dependent methionine synthase, Methods in Enzymology,380,152-169. PMID:15051336 
  37. Matthews, R. G., Smith, A. E., Zhou, Z. H. S., Taurog, R. E., Bandarian, V., Evans, J. C., Ludwig, M. L. (2003) Cobalamin-dependent and cobalamin-indepenent methionine synthases:  Are there two solutions to the same chemical problem?, Helv. Chim. Acta, 86, 3939-3954. 
  38. Bandarian, V., Ludwig, M. L., and Matthews, R. G. (2003) Factors modulating conformational equilibria in large modular proteins:  A case study with cobalamin-dependent methionine synthase, Proc. Natl. Acad. Sci. USA, 100, 8156-8163. PMCID: PMC166199
  39. Bandarian, V., and Reed, G. H. (2002) Analysis of electron paramagnetic resonance spectrum of a radical intermediate in the coenzyme B12-dependent ethanolamine ammonia-lyase reaction with S-propanolamine, Biochemistry, 41, 8580-8588. PMID:12093274
  40. Bandarian, V., Pattridge, K. A., Lennon, B. W., Huddler, D. P., Matthews, R. G., and Ludwig, M. L.  (2002) Domain alternation switches B12-dependent methionine synthase to the activation conformation, Nature Struct. Biol., 9, 53-56. PMID:11731805
  41. Bandarian, V., and Matthews, R. G. (2001) Quantitation of rate enhancements attained by the binding of cobalamin to methionine synthase, Biochemistry, 40, 5056-5064. PMID:11305922
  42. LoBrutto, R., Bandarian, V., Magnusson, O. Th., Chen, X., Schramm, V. L., and Reed, G. H. (2001) 5’-Deoxyadenosine contacts the substrate radical intermediate in the active site of ethanolamine ammonia-lyase:2H and 13C Electron nuclear double resonance studies, Biochemistry,40, 9-14. PMID:11141051
  43. Miller, J., Bandarian, V., Reed, G. H., and Frey, P. A. (2001)  Inhibition of lysine 2,3-aminomutase by the alternative substrate 4-thialysine and characterization of the 4-thialysyl radical intermediate, Arch. Biochem. Biophys., 387, 281-287. PMID:11370852
  44. Bandarian, V. and Reed, G. H. (2000) Isotope effects in the transient phases of the reaction catalyzed by ethanolamine ammonia-lyase: determination of the number of exchangeable hydrogens in the enzyme-cofactor complex, Biochemistry, 39, 12069-12075. PMID:11009622
  45. Wu, W., Booker, S., Lieder, K. W., Bandarian, V., Reed, G. H. (2000) Lysine 2,3-aminomutase and trans-4,5-dehydrolysine: Characterization of an allylic analogue of a substrate-based radical in the catalytic mechanism, Biochemistry, 39, 9561-9570. PMID:10924153
  46. Abend, A., Bandarian, V., Reed, G. H., and Frey, P. A  (2000) Identification of cis- ethanesemidione as the organic radical derived from glycolaldehyde in the suicide inactivation of dioldehydrase and of ethanolamine ammonia-lyase, Biochemistry, 39, 6250-6257. PMID:10496987
  47. Chang, C-w. T., Johnson, D. A., Bandarian, V., Zhou, H., LoBrutto, R., Reed, G. H., and Liu, H.-w. (2000) Characterization of a unique coenzyme B6 radical in the ascarylose biosynthetic pathway, J. Amer. Chem. Soc., 122, 4239-4240. 
  48. Bandarian, V., and Reed, G. H. (1999) Ethanolamine ammonia-lyase, in Chemistry and Biochemistry of B12, John Wiley and Sons, Inc., Editor: Ruma Banerjee, 811-833.  
  49. Bandarian, V., Poyner, R. R., and Reed, G. H. (1999) Hydrogen atom exchange between 5'-deoxyadenosine and hydroxyethylhydrazine during the single turnover inactivation of ethanolamine ammonia-lyase, Biochemistry,38, 12403–12407. PMID:10493808
  50. Bandarian, V., and Reed, G. H. (1999) Hydrazine cation radical in the active site of ethanolamine ammonia-lyase: mechanism-based inactivation by hydroxyethylhydrazine, Biochemistry,38, 12394–12402. PMID:10493807
  51. Abend, A., Bandarian, V., Nitsche, R., Stupperich, E., Rétey, J., and Reed, G. H. (1999) Ethanolamine ammonia-lyase has a “base-on” binding mode for coenzyme B(12), Arch Biochem Biophys,370, 138–141. PMID:10496987
  52. Abend, A., Nitsche, R., Bandarian, V., Stupperich, E., and Rétey, J. (1998) Dioldehydrase binds coenzyme B12 in the base-on mode - ESR investigations on cob(II)alamin, Angewandte Chemie, International Ed. in English,37, 625–627.
  53. Frey, P. A., Reed, G. H., Moss, M. L., Petrovich, R. M., Ballinger, M. D., Lieder, K. W., Wu, W., Chang, C. H., Bandarian, V., Ruzicka, F. J., LoBrutto, R., and Beinert, H. (1998) in Vitamin B1 2and B12 Proteins.  Proceedings of the 4th European Symposium on Vitamin B12 and B12 Proteins, pp 397-408, Wiley-VCH, Weinheim
  54. Ballou, D., Gassner, G. T., Johnson, D. A., Liu, H.-w., Bandarian, V., Ruzicka, F., and Reed, G. H. (1997) in Flavins and Flavoproteins (Stevenson, K. J., Massey, V., and Williams, J., C. H., Eds.) pp. 889-898, University of Calgary Press, Calgary.
  55. Johnson, D. A., Gassner, G. T., Bandarian, V., Ruzicka, F. J., Ballou, D. P., Reed, G. H., and Liu, H. W. (1996) Kinetic characterization of an organic radical in the ascarylose biosynthetic pathway, Biochemistry,35, 15846–15856. PMID:8961949
  56. Xia, B., Cheng, H., Bandarian, V., Reed, G. H., and Markley, J. L. (1996) Human ferredoxin: overproduction in Escherichia coli, reconstitution in vitro, and spectroscopic studies of iron-sulfur cluster ligand cysteine-to-serine mutants, Biochemistry,35, 9488–9495. PMID:8755728
  57. Spangler, N. J., Lindahl, P. A., Bandarian, V., and Ludden, P. W. (1996) Spectroelectrochemical characterization of the metal centers in carbon monoxide dehydrogenase (CODH) and nickel-deficient CODH from Rhodospirillum rubrum, J Biol Chem.,271, 7973–7977. PMID:8626477
  58. Bandarian, V., Poehner, W. J., and Grover, S. D. (1992) Metabolite Activation of Crassulacean Acid Metabolism and C4 Phosphoenolpyruvate Carboxylase, Plant Physiol,100, 1411–1416. PMCID: PMC1075800
Last Updated: 7/9/20