Harris Research Group
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News & Updates
- October 22, 2024:Jay wins the Society for Applied Spectroscopy Award for Distinguished Service! Congrats Jay!!
- October 22, 2024: Jay wins one of the two SAS Early Career Travel Awards from the Society for Applied Spectroscopy, supporting his travel to FACSS/SciX to give a talk on his research! Congrats Jay!!
- August 20, 2024: At the Denver ACS Meeting, Joel received the ACS Division of Analytical Chemistry, the Roland F. Hirsch Award for Distinguished Service in the Advancement of Analytical Chemistry.
- April 17, 2024: At the Chemistry Department Awards Program, Aric was named a Phillips Senior Scholar, and Clista was acknowledged as a Chemistry Honors Graduate. Congratulations!
- April 9, 2024: Clista’s poster “Raman Spectroscopy Characterization of Antibody-ligand Association at Supported Phospholipid Bilayers” was selected as one of two Best STEM Posters in the UROP Spring Symposium. Her poster will be on display in the Marriott Library.
- April 4, 2024: Clista is inducted into the University of Utah Beehive Honor Society, the oldest and most prestigious honor society at the U. 2024 Beehive Honor Society
- November 14, 2023: Aric wins an EAS Undergraduate Student Research Award at the Eastern Analytical Symposium in Plainsboro, NJ! Congratulations Aric!
- October 10, 2023: Maran wins an FACSS Student Poster Award at SciX in Reno! Congratulations Maran!
- October 8, 2023: Clista wins the 2023 SAS Undergraduate Student Award! Congratulations Clista!
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April 20, 2023: At the Chemistry Department Awards Program, several of the lab members were honored: Dawson won a Walter D. & Grace G. Bonner Memorial Award, Dawson won the ACS Physical Division Award, Maran won a Leon Watters Memorial Award, Aric won the College of Science Dean’s Scholarship, Clista won a the College of Science Promise Scholarship and the Department of Chemistry Tuition Benefit Scholarship, and Aric won the Ted Eyring Undergraduate Scholarship, and finally Grant was the winner of the highest honor given by the department for an outstanding Ph.D. dissertation: Cheves Walling Graduate Research Award. Congratulations all! What an afternoon!
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March 23, 2023: Maran Sardoni joins the lab as an Undergraduate Research Assistant. Welcome Maran!
Recent Research Highlights
“Surface-Area Enhanced Raman Spectroscopy of DNA in Porous Silica: A Quantitative and Reproducible Alternative to Plasmonic-Based SERS,” Grant J. Myres, Jay P. Kitt, and Joel M. Harris, Analytical Chemistry, 96, 7679 (2024).
"Ramen Scattering Reveals Ion-Dependent G-Quadraplex Formation in the 15-mer Thrombin-Binding
Aptamer upon Association with α-Thrombin," Grant J. Myres, Jay P. Kitt, and Joel M. Harris, Analytical Chemistry, 95, 16160-16168
(2003).
"Stable Immobilization of DNA to Silica Surfaces by Sequential Michael Addition Reactions
Developed with Insights from Confocal Raman Microscopy", Grant J. Myres and Joel M. Harris, Analytical Chemistry, 95, 3499–3506 (2023)
“Evaluating the Effect of Ionic Strength on PNA:DNA Duplex Formation Kinetics,” Colin S. Swenson, Hershel H. Lackey, Eric J. Reece, Joel M. Harris, Jennifer M. Heemstra, and Eric M. Peterson, RSC Chemical Biology, 2, 1249 (2021).
“Confocal-Raman Microscopy Enables Label-Free, Quantitative, and Structurally-Informative Detection of DNA Hybridization at Porous Silica Surfaces,” Grant J. Myres, Eric M. Peterson, and Joel M. Harris, Analytical Chemistry, 93, 7978 (2021).
“Hybrid-Lipid Bilayers Induce n-Alkyl-Chain Order in Reversed-Phase Chromatographic Surfaces, Impacting their Shape Selectivity for Aromatic Hydrocarbon Partitioning,” Maryam Zare, Jay P. Kitt, Xin Wen, Emily Heider, Joel M. Harris, Analytical Chemistry, 93, 4118(2021).
“Single-Molecule Kinetics Show DNA Pyrimidine Content Strongly Affects RNA:DNA and TNA:DNA Heteroduplex Dissociation Rates,” Hershel Lackey, Zhe Chen, Joel M. Harris, Eric M. Peterson, and Jennifer M. Heemstra, ACS Synthetic Biology, 9, 249 (2020).
"Hybrid-Supported Bilayers Formed with Mixed-Charge Surfactants on C18-Functionalized Silica Surfaces," Maryam Zare, Jay P. Kitt, and Joel M. Harris, Langmuir, 36, 7609-7618 (2020)
“Probing the Mechanism of Structure-Switching Aptamer Assembly by Super-Resolution Localization of Individual DNA Molecules,” Hershel H. Lackey, Eric M. Peterson, Joel M. Harris, and Jennifer M. Heemstra, Analytical Chemistry, 92, 6909 (2020).
"Confocal Raman Microscopy Investigation of Phospholipid Monolayers Deposited on Nitrile-Modified Surfaces in Porous Silica Particles," David A. Bryce, Jay P. Kitt, Grant J. Myres, and Joel M. Harris, Langmuir, 36, 4071 (2020).
“Super-Resolution Imaging of Competitive Unlabeled DNA Hybridization Reveals the Influence of Fluorescent Labels on Duplex Formation and Dissociation Kinetics,” Eric M. Peterson, Eric J. Reece, Wenyuan Li, and Joel M. Harris, Journal of Physical Chemistry B, 123, 10746-10756 (2019); selected for the ACS Virtual Issue on Super-Resolution Far-Field Optical Microscopy.
“Confocal Raman Microscopy Investigation of Self-Assembly of Hybrid Phospholipid Bilayers within Individual Porous Silica Chromatographic Particles,” Jay P. Kitt, David A. Bryce, Shelley D. Minteer, and Joel M. Harris, Analytical Chemistry, 91, 7790 (2019)
“Thermostability Trends of TNA:DNA Duplexes Reveal Strong Purine Dependence,” Hershel Lackey, Eric M. Peterson, Zhe Chen, Joel M. Harris, and Jennifer M. Heemstra, Jennifer, ACS Synthetic Biology, 8, 1144 (2019)
“Single-Molecule Kinetic Investigation of Cocaine-Dependent Split-Aptamer Assembly,” Frances D. Morris, Eric M. Peterson, Jennifer M. Heemstra, and Joel M. Harris, Analytical Chemistry, 90, 12964 (2018).
“Confocal Raman Microscopy for Label-Free Detection of Protein-Ligand Binding at Nanopore-Supported Phospholipid Bilayers,” David A. Bryce, Jay P. Kitt, and Joel M. Harris, Analytical Chemistry, 90, 11509 (2018).
“Confocal Raman Microscopy for In-situ Measurement of Phospholipid-Water Partitioning into Model Phospholipid Bilayers within Individual Chromatographic Particles,” Jay P. Kitt, David A. Bryce, Shelley D. Minteer, and Joel M. Harris, Analytical Chemistry, 90, 7048 (2018).
“Identification of Individual Immobilized DNA Molecules by their Hybridization Kinetics Using Single-Molecule Fluorescence Imaging,” Eric M. Peterson and Joel M. Harris, Analytical Chemistry, 90, 5007 (2018).
“Confocal-Raman Microscopy Characterization of Supported Phospholipid Bilayers Deposited on the Interior Surfaces of Chromatographic Silica,” David A. Bryce, Jay P. Kitt, and Joel M. Harris, Journal of the American Chemical Society, 140, 4071 (2018).